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Matthew Perry passed away due to a Ketamine overdose

Matthew Perry passed away
Matthew Perry passed away

Matthew Perry passed away due to a Ketamine overdose

 

Matthew Perry passed away due to a Ketamine overdose

Matthew Perry passed away due to a Ketamine overdose.Dr. Shaunak Ajinkya, a Consultant Psychiatrist at Kokilaben Dhirubhai Ambani Hospital in Mumbai, assures that when used therapeutically and under controlled conditions, ketamine is safe. The risks arise mainly from unauthorized use.

      • Recent news reports suggest that Matthew Perry, the beloved Friends star, passed away due to the ‘acute effects’ of ketamine, a drug used in anesthesia and certain antidepressants. Unfortunately, some individuals misuse it as a party drug.

        • Matthew Perry had been undergoing ketamine infusion therapy for depression, receiving treatments every other day for a period. However, he had reduced the frequency, and his last known infusion was about a week and a half before his death.

          • The Los Angeles County medical examiner suggested that a possible ketamine overdose led to ‘cardiovascular overstimulation and respiratory depression.’ Perry, who had diabetes and chronic obstructive pulmonary disease, may have experienced complications related to airflow blockage and breathing problems due to the drug.”

        Matthew Perry passed away due to a Ketamine overdose

            • “Dr. Shaunak Ajinkya, a Psychiatrist at Kokilaben Dhirubhai Ambani Hospital in Mumbai, explains that in India, Ketamine is classified as a Schedule X drug. This means the prescribing doctor carefully regulates and monitors it on a case-by-case basis. It is considered safe when used as a therapeutic intervention under proper supervision. The risks come into play only when the drug is used without authorization.”

          What is Ketamine?

              • In 1962, the American chemist Calvin L Stevens created it in his lab. Originally, it served as an anesthetic for both animals and humans in the late 1960s and was even used in surgeries during the Vietnam War.

                • Derived from a hallucinogenic drug called Phencyclidine (PCP), Ketamine works by blocking the NMDA receptor in the brain and spinal cord while increasing a brain chemical called glutamate. In simpler terms, it stops the transmission of pain in the spinal cord and activates the brain’s reward pathways.

                  • This led to Ketamine being used in pain management. In the past decade or so, it has shown promise as a new treatment for severe depression due to its euphoric qualities, and doctors have started prescribing it to help lift patients out of their lows.

                Why is it susceptible to substance abuse?

                    • Well, the drug induces a ‘dissociative’ effect, leading individuals to hallucinate and experience an altered reality—a kind of high known as a ‘K-hole.’ Because it’s a clear liquid and difficult to detect, and even the white powder form can be easily dissolved, some people started using it as a date rape drug. Nowadays, it’s even available in the form of nasal sprays.

                  Matthew Perry passed away due to a Ketamine overdose

                  What happens when there’s a Ketamine overdose and how does it affect the body?

                      • Well, because Ketamine is a relaxant, it can make breathing difficult, causing shallow breaths and even lung collapse. This puts extra strain on the heart, speeding up your heart rate and blood pressure. If your arteries aren’t in good shape, they may struggle to keep up, leading to stress and the risk of sudden cardiac arrest.

                        • Ketamine is also harmful to the urinary bladder and liver. Taking unregulated high doses can even result in schizophrenia and the development of drug dependence. Sadly, the danger increases when Ketamine is mixed with alcohol, which might have been a factor in Perry’s case.

                      Matthew Perry passed away due to a Ketamine overdose

                      How does Ketamine work for depression?

                      In 2006, scientists at the National Institutes of Health discovered that a dose of Ketamine through an IV could effectively ease severe depression within just a few hours, which was quicker than other treatments available. Then, in 2019, the US Food and Drug Administration (FDA) gave the green light to a nasal spray as the first antidepressant that’s based on Ketamine.

                      HOW IS KETAMINE EFFECTIVE IN DEPRESSION?

                      Ketamine has shown remarkable effectiveness in treating depression. Back in 2006, scientists at the National Institutes of Health discovered that a dose of ketamine administered through an IV could bring relief from severe depression within a few hours, surpassing the speed of other available treatments. Fast forward to 2019, the US Food and Drug Administration (FDA) gave the thumbs up for a nasal spray, marking the first-ever antidepressant derived from ketamine.

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